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Quantitative analyses of morphological changes of cell growth by graphics computer techniques. A methodologic study

✍ Scribed by V.L. Weimar; K.H. Haraguchi


Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
750 KB
Volume
60
Category
Article
ISSN
0003-2697

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✦ Synopsis


A computerized image analysis system is described for quantitation of changes in cell morphology for use in the bioassay of certain types of growth factors in organ cultures of connective tissue cells.

Eight response variables, indicative of cell growth, were measured (area of cell, area of nucleus, area of cytoplasm, length of the cell, lengths of the major and minor axes, number of nucleoli per cell, and total area of nucleoli per cell).