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Quantitation of hemoglobin in single erythrocytes with and without fetal hemoglobin

โœ Scribed by Dr. J. Meletis; X. Yataganas; E. Papavasiliou; G. Vaiopoulos; Ph. Fessas


Book ID
114790744
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
518 KB
Volume
39
Category
Article
ISSN
0902-4441

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Variation in the level of fetal hemoglobin (HbF) accounts for much of the clinical heterogeneity observed in patients with sickle cell disease (SCD). The HbF level has emerged as an important prognostic factor in both sickle cell pain and mortality, and a % HbF of 10-20% has been suggested as a thre