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Quantitation of gentamicin sulfate in injectable solutions by capillary electrophoresis

✍ Scribed by Cheryl L. Flurer; Karen A. Wolnik

Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
365 KB
Volume
663
Category
Article
ISSN
1873-3778

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The renal accumulation of alpha2u-globulin has been implicated in the tumorigenicity of many nongenotoxic chemicals to the kidney of the male rat. Several chemicals inducing renal tumors in the male rat were shown to bind to alpha2u-globulin. This binding impairs the renal degradation of alpha2u-glo