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Quantitation of biliary excretion of drugs in man

✍ Scribed by Dujovne, Carlos A; Gustafson, J H; Dickey, R A


Book ID
109843178
Publisher
Nature Publishing Group
Year
1982
Tongue
English
Weight
577 KB
Volume
31
Category
Article
ISSN
0009-9236

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The objective of this study is to predict clearance of drugs in humans from animals which are excreted in the bile. Clearance (CL) of eight drugs known to be excreted in the bile were randomly selected from the literature. Scaling of CL was performed using at least three animal species. Using simple