Analysis of benzo[a]pyrene diol epoxide-
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An V. Willems; Dieter L. Deforce; Elfriede G. Van den Eeckhout; Willy E. Lambert
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Article
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2002
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John Wiley and Sons
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English
β 215 KB
π 2 views
## Abstract Benzo[__a__]pyrene diol epoxide (BPDE) was reacted __in vitro__ with (2'βdeoxy)nucleotides and with calf thymus DNA. The modified DNA was enzymatically hydrolyzed to the 5'βmonophosphate nucleotides using deoxyribonuclease I (DNAβase I), nuclease P1 and snake venom phosphodiesterase (SV