Quantitation of astrocytes in the molecular layer of the dentate gyrus in schizophrenic patients
β Scribed by Manuel F. Casanova; Richard Saunders; Jan Stevens; Joel E. Kleinman
- Book ID
- 118318304
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 86 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0006-3223
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## Abstract Numerous ectopic granule cells are found in the molecular layer of the dentate gyrus in NZB/BINJ and dreher mutant mice. These ectopic neurons occur either singly or in small clusters. In contrast, few ectopic granule cells are seen in the dentate molecular layer of C57BL/6J mice and dr
Reorganization of the adult dentate gyrus following unilateral entorhinal cortex lesion (ECL) is a well-established model for studying mechanisms of trauma-induced neuronal plasticity. The lesion induces deafferentiation of the outer molecular layer, which is accompanied by a strong astroglial react