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Quantitation of adenosine A2A receptors availability in Parkinson's Disease patients with and without dyskinesias with [11C]SCH442416 PET using spectral analysis

✍ Scribed by Subrata K. Bose; Anil F. Ramlackhansingh; Imtiaz Ahmed; Nicola Pavese; David J. Brooks; Federico E. Turkheimer

Book ID
119331429
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
614 KB
Volume
52
Category
Article
ISSN
1053-8119

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## Abstract We used [^11^C]raclopride (RACLO) and positron emission tomography (PET) to study longitudinally striatal dopamine D~2~ receptor binding in nine patients with Parkinson's disease (PD) at an early drug‐naive stage and 3–5 years later, when motor fluctuations had appeared in seven of them