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Quantifying Protein-Ligand Binding Constants using Electrospray Ionization Mass Spectrometry: A Systematic Binding Affinity Study of a Series of Hydrophobically Modified Trypsin Inhibitors

โœ Scribed by Dragana Cubrilovic, Adam Biela, Frank Sielaff, Torsten Steinmetzer, Gerhard Klebe, Renato Zenobi


Book ID
118303471
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
679 KB
Volume
23
Category
Article
ISSN
1044-0305

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โœ Armelle Buzy; Edward M. Ryan; Keith R. Jennings; David N. Palmer; David E. Griff ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 664 KB

Ceroid lipofuscinosiiprotein (CLP), the major accumulating protein in several forms of ceroid lipofuscinosis, has an amino acid sequence that is identical to that of the Fo subunit c of normal bovine ATP synthase. Electrospray ionization mass spectrometry (ESI-MS) has shown that ovine CLP and normal