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Quantifying Interactions of a Membrane Protein Embedded in a Lipid Nanodisc using Fluorescence Correlation Spectroscopy

✍ Scribed by Ly, Sonny; Bourguet, Feliza; Fischer, Nicholas O.; Lau, Edmond Y.; Coleman, Matthew A.; Laurence, Ted A.

Book ID
122493582
Publisher
Biophysical Society
Year
2014
Tongue
English
Weight
559 KB
Volume
106
Category
Article
ISSN
0006-3495

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## Abstract Nanolipoprotein particles (NLPs) represent a unique nanometer‐sized scaffold for supporting membrane proteins (MP). Characterization of their dynamic shape and association with MP in solution remains a challenge. Here, we present a rapid method of analysis by fluorescence correlation sp