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Quantification ofN-acetyl-l-aspartic acid in urine by isotope dilution gas chromatography-mass spectrometry

โœ Scribed by R. I. Kelley; J. N. Stamas


Publisher
Springer
Year
1992
Tongue
English
Weight
637 KB
Volume
15
Category
Article
ISSN
0141-8955

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## Abstract __N__โ€acetylaspartic acid (NAA) is a specific urinary marker for Canavan disease, an autosomal recessive leukodystrophy. We developed a โ€˜dilute and shootโ€™ stable isotope dilution liquid chromatography tandem mass spectrometry (LCโ€MS/MS) method for determination of NAA in urine. Deuterat