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Quantification of the familial contribution to juvenile idiopathic arthritis

✍ Scribed by Sampath Prahalad; Andrew S. Zeft; Richard Pimentel; Bronte Clifford; Bernadette McNally; Geraldine P. Mineau; Lynn B. Jorde; John F. Bohnsack

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
92 KB
Volume
62
Category
Article
ISSN
0004-3591

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## Abstract ## Objective To investigate whether single‐nucleotide polymorphisms (SNPs) within the genes __PRF1, GZMB, UNC13D__, and __Rab27a,__ which are involved in natural killer cell dysfunction and known to contribute to the risk of hemophagocytic lymphohistiocytosis (HLH), confer an increased