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Quantification of rare allelic variants from pooled genomic DNA

✍ Scribed by Druley, Todd E; Vallania, Francesco L M; Wegner, Daniel J; Varley, Katherine E; Knowles, Olivia L; Bonds, Jacqueline A; Robison, Sarah W; Doniger, Scott W; Hamvas, Aaron; Cole, F Sessions


Book ID
109935388
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
197 KB
Volume
6
Category
Article
ISSN
1552-4450

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## Abstract A combination of common and rare variants is thought to contribute to genetic susceptibility to complex diseases. Recently, next‐generation sequencers have greatly lowered sequencing costs, providing an opportunity to identify rare disease variants in large genetic epidemiology studies.