Quantification of pramipexole in human plasma by liquid chromatography tandem mass spectrometry using tamsulosin as internal standard
✍ Scribed by Ramakrishna V. S. Nirogi; Vishwottam Kandikere; Wishu Shrivastava; Koteshwara Mudigonda; Santosh Maurya; Devender Ajjala
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 247 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0269-3879
- DOI
- 10.1002/bmc.864
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A simple, rapid, sensitive and specific liquid chromatography-tandem mass spectrometry method was developed and validated for quantification of hydrochlorothiazide (I), a common diuretic and anti-hypertensive agent. The analyte and internal standard, tamsulosin (II) were extracted by liquid-liquid e