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Quantification of l-arginine, asymmetric dimethylarginine and symmetric dimethylarginine in human plasma: A step improvement in precision by stable isotope dilution mass spectrometry

✍ Scribed by Jens Martens-Lobenhoffer; Stefanie M. Bode-Böger


Book ID
119289240
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
252 KB
Volume
904
Category
Article
ISSN
1873-376X

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Determination of arginine and asymmetric
✍ Jens Martens-Lobenhoffer; Olga Krug; Stefanie M. Bode-Böger 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 172 KB

## Abstract Arginine (ARG) is a substrate for endogenous nitric oxide (NO) production whereas its metabolite, asymmetric dimethylarginine (ADMA), acts as an inhibitor. Sufficient NO production is essential for cardiovascular key functions, thus elevated concentration levels of ADMA are related to a