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Quantification of intact carboplatin in human plasma ultrafitrates using hydrophilic interaction liquid chromatography–tandem mass spectrometry and its application to a pharmacokinetic study

✍ Scribed by Ito, Hajime; Yamaguchi, Hiroaki; Fujikawa, Asuka; Shiida, Narumi; Tanaka, Nobuaki; Ogura, Jiro; Kobayashi, Masaki; Yamada, Takehiro; Mano, Nariyasu; Iseki, Ken

Book ID
122778468
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
594 KB
Volume
917-918
Category
Article
ISSN
1873-376X

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Quantification of doxazosin in human pla
Quantification of doxazosin in human plasma using hydrophilic interaction liquid chromatography with tandem mass spectrometry
✍ Hye Young Ji; Eun Jeong Park; Kang Choon Lee; Hye Suk Lee 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 632 KB

## Abstract Hydrophilic interaction LC with MS/MS (HILIC‐MS/MS) was described as a rapid, sensitive, and selective method for the quantification of doxazosin in human plasma. Doxazosin and cisapride (internal standard) were extracted from human plasma with ethyl acetate at alkaline pH and analyzed