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Quantification of human T-cell lymphotropic virus type 1 proviral load by quantitative competitive polymerase chain reaction

✍ Scribed by Björn Albrecht; Nathaniel D. Collins; Garret C. Newbound; Lee Ratner; Michael D. Lairmore


Book ID
114140641
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
802 KB
Volume
75
Category
Article
ISSN
0166-0934

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Adult T-cell leukemia (ATL) is a neoplasm of mature helper (CD4) T lymphocytes, and human T-cell lymphotropic virus type-I (HTLV-I) has been suggested to be the causative virus of ATL. HTLV-I integrates its proviruses into random sites in host chromosomal DNA. Clonal integration has been observed in