Quantification of human high molecular weight kininogen by immunoblotting with a monoclonal anti-light chain antibody
β Scribed by Sesha Reddigari; Allen P. Kaplan
- Book ID
- 118901697
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 564 KB
- Volume
- 119
- Category
- Article
- ISSN
- 0022-1759
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
High-molecular-weight kininogen, a nonenzymatic glycoprotein of the intrinsic blood coagulation system, is proteolytically cleaved by kallikrein as an early event in the activation of this system. The light chain of cleaved kininogen retains the ability to form specific noncovalent complexes with pr
## Abstract The lack of efficacy of available therapies for the treatment of malignant melanoma has emphasized the need to develop novel therapeutic strategies to prevent melanoma growth. We have tested whether the antiβHMWβMAA mAb 225.28S is able to inhibit human melanoma tumor growth in SCID mice