Insulin resistance affects sustained virological response (SVR) in chronic hepatitis C. To know whether adding metformin to standard antiviral treatment improves SVR, we conducted a prospective, multicentered, randomized, double-blinded, placebo-controlled trial in 19 Spanish hospitals, including 12
Quantification of hepatitis C virus in patients treated with peginterferon-alfa 2a plus ribavirin treatment by COBAS TaqMan HCV test
โ Scribed by T. Kanda; F. Imazeki; Y. Yonemitsu; S. Mikami; N. Takada; T. Nishino; M. Takashi; A. Tsubota; K. Kato; N. Sugiura; A. Tawada; S. Wu; T. Tanaka; S. Nakamoto; R. Mikata; M. Tada; T. Chiba; T. Kurihara; M. Arai; K. Fujiwara; F. Kanai; O. Yokosuka
- Book ID
- 108886551
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 150 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1352-0504
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## Abstract Variation at the ILโ28B locus was recently reported to be a significant predictive factor of viral response to pegylatedโinterferon plus ribavirin combination therapy against chronic hepatitis C. Predictive factors for the effect of therapy, including ILโ28B polymorphism rs8099917 and v
The objective of this study is to determine the efficacy and safety of peginterferon alfa-2a (40 KD)/ribavirin in patients with advanced fibrosis. Data from 341 genotype 1/4 patients (99 with bridging fibrosis/cirrhosis) treated for 48 weeks and 1547 genotype 2/3 patients (380 with bridging fibrosis