Quantification of hepatitis B e antigen between Elecsys HBeAg and Architect HBeAg assays among patients infected with hepatitis B virus
✍ Scribed by Maylin, Sarah; Boyd, Anders; Martinot-Peignoux, Michelle; Delaugerre, Constance; Bagnard, Georges; Lapalus, Martine; Zoulim, Fabien; Lavocat, Fabien; Marcellin, Patrick; Simon, François; Girard, Pierre-Marie; Lacombe, Karine
- Book ID
- 121993536
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 286 KB
- Volume
- 56
- Category
- Article
- ISSN
- 1386-6532
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## Abstract Hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) is responsible for viral persistence. This study aimed to investigate the serum surrogate markers for cccDNA and to evaluate the intrahepatic viral events associated with disease activity in HBeAg‐negative chronic hepatitis
Hepatitis B e antibody (HbeAb) and hepatitis B virus (HBV) DNA positive chronic hepatitis is a clinical entity, distinct from classical hepatitis B e antigen (HbeAg) positive chronic hepatitis B. Our aim was to evaluate the long-term therapeutic efficacy of the combination of interferon alpha-2b and