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Quantification of glucocorticoid receptor (GR) activation and translocation: A novel method

โœ Scribed by Petrov, A.; Burke, N.; Neely, C.M.; Robinson, M.L.; Watkins, S.; Ameredes, B.T.; Calhoun, W.J.


Book ID
119491401
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
114 KB
Volume
111
Category
Article
ISSN
1097-6825

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Activation of the glucocorticoidโ€“recepto
โœ Thomas J. Schmidt; Carol A. Barnett; Gerald Litwack ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 905 KB

## Abstract A crucial step in the interaction of glucocorticoids with target cells is the activation step, which involves a conformational change in the cytoplasmic glucocorticoidโ€“receptor protein complexes and facilitates their binding to the cell nucleus. Activation can be quantified by measuring