Nasopharyngeal carcinomas (NPCs) of non-keratinizing type are strongly associated with Epstein-Barr virus (EBV). EBV and its gene products induce the synthesis and/or release of transforming growth factor 1 (TGF-1) from human cells and platelets. TGF-1 is an immunosuppressive cytokine, and many t
✦ LIBER ✦
Quantification of Epstein-Barr virus DNA load, interleukin-6, interleukin-10, transforming growth factor-β1 and stem cell factor in plasma of patients with nasopharyngeal carcinoma
✍ Scribed by Eng-lai Tan; G Selvaratnam; R Kananathan; Choon-kook Sam
- Book ID
- 115010865
- Publisher
- BioMed Central
- Year
- 2006
- Tongue
- English
- Weight
- 277 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1471-2407
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## Abstract Chronic active Epstein–Barr virus (EBV) infection is a chronic mononucleosis syndrome associated with clonal proliferation of EBV‐carrying T‐/natural killer (NK)‐cells. High levels of circulating EBV and activated T‐cells are sustained during the prolonged disease course, whereas it is
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