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Quantification of dideoxycytidine in human plasma by gas chromatography/mass spectrometry

✍ Scribed by Felix R. Rubio; Theodore Crews; William A. Garland; Elaine K. Fukuda

Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
510 KB
Volume
17
Category
Article
ISSN
1076-5174

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## Abstract A rapid, selective and sensitive method for the determination of lamivudine in human plasma was developed using hydrophilic interaction chromatography‐MS/MS. This method involved protein precipitation with acetonitrile as sample preparation procedure. Lamivudine and famotidine (internal