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Quantification of bone lytic lesions and prognosis in myelomatosis

✍ Scribed by Gramont, Aimery ;Benitez, Oscar ;Brissaud, Philippe ;Krulik, Marcel ;Hubert, Dominique ;Sirinelli, Agnès ;Smadja, Nicole ;Debray, Jacques

Book ID
114790282
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
348 KB
Volume
34
Category
Article
ISSN
0036-553X

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## Abstract Osteopontin (OPN), a secreted phosphoprotein involved in immune regulation and bone homeostasis, is a major component of bone, the natural habitat of long‐lived plasma cells and multiple myeloma (MM). We show that only some MM cell lines and primary patient samples express OPN at high l