Quantification of aortic regurgitation and stroke volume by CMR - variation due to slice plane position. It matters where you measure!
✍ Scribed by Christian R Hamilton-Craig; Peter J Cawley; Abhishek Chaturvedi; Gregory J Wilson; William Kerwin; Catherine M Otto; Jeffrey H Maki
- Publisher
- BioMed Central
- Year
- 2011
- Tongue
- English
- Weight
- 252 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1097-6647
No coin nor oath required. For personal study only.
✦ Synopsis
Aortic regurgitation by CMR has been assessed in various locations, including sinus of valsalva (SOV), sinotubular junction (STJ), and ascending aorta (ASC). Variability in obtained measurements and interchangeability of these locations and methods in patients with varying valvular disease severity is unknown. We sought to determine the most appropriate aortic level for accurate phase contrast quantitative (Q) flow measurement of forward and backward flow and calculation of Qp:Qs in patients with valvular heart disease.
Methods and materials
57 patients with valvular disease (31 aortic regurgitation (AR), 25 mitral regurgitation (MR), 1 both) were imaged at 1.5T using Q flow at 3 ascending aorta locations: sinus of valsalva (SOV), sinotubular junction (STJ), tubular ascending aorta 1 cm above STJ (ASC). Pulmonary artery (PA) Q flow was performed at two adjacent locations 1 cm apart. No patient had intracardiac shunt. Blinded analysis was performed by two expert readers with SCMR level 2 and 3 experience. Net stroke volume (SV), forward volume (FV) and backward volume (BV) were measured and analyzed by Student t-test.