## Abstract In order to assess the efficacy of interferon‐α on hepatitis C viral RNA in patients with chronic hepatitis C, we analyzed the levels of HCV RNA in sera and liver tissues of 16 patients pre‐ and posttreatment using a semiquantitative polymerase chain reaction method. Fifteen of 16 patie
Quantification and genotyping of serum HCV-RNA in patients with chronic hepatitis C undergoing interferon treatment
✍ Scribed by G. Gerken; P. Knolle; S. Jakobs; K.-H. Meyer zum Büschenfelde
- Publisher
- Springer Vienna
- Year
- 1997
- Tongue
- English
- Weight
- 194 KB
- Volume
- 142
- Category
- Article
- ISSN
- 1432-8798
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## Abstract Hepatitis C virus (HCV) replication was assessed before and during alpha‐interferon (IFN) treatment in 22 anti‐HCV positive patients with posttransfusion or sporadic chronic hepatitis (CH). Eleven patients were “responders” and 11 patients “non‐responders” to IFN. Thirteen anti‐HCV nega
Hepatitis C virus RNA as detected by reverse transcription and nested polymerase chain reaction was monitored in 16 patients with chronic hepatitis C treated with interferon. Hepatitis C virus R N A became undetectable after 4 to 8 wk of interferon administration in 13 of the 16 patients. During 6 m
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