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Quantification and anatomic distribution of choroidal abnormalities in patients with type I neurofibromatosis

✍ Scribed by Shunsuke Nakakura; Kunihiko Shiraki; Takaharu Yasunari; Yoko Hayashi; Shinsuke Ataka; Takeya Kohno


Book ID
106097347
Publisher
Springer-Verlag
Year
2005
Tongue
English
Weight
210 KB
Volume
243
Category
Article
ISSN
0065-6100

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The neurofibromatosis type I gene encodes a protein, neurofibromin, which may function as a tumor suppressor gene product. Recent studies have demonstrated loss of neurofibromin in tumors from NF I and non-NF I patients, including neurofibrosarcomas. neuroblastomas and malignant melanomas. Since ne