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QuantiFERON to diagnose infection by Mycobacterium tuberculosis: Performance in infants and older children

✍ Scribed by Blandinières, Adeline; de Lauzanne, Agathe; Guérin-El Khourouj, Valérie; Gourgouillon, Nadège; See, Hélène; Pédron, Béatrice; Faye, Albert; Sterkers, Ghislaine


Book ID
125454050
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
579 KB
Volume
67
Category
Article
ISSN
0163-4453

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IL-10 regulates the balance of an immune response between pathogen clearance and immunopathology. We show here that __Mycobacterium tuberculosis__ (__Mtb__) infection in the absence of IL-10 (IL-10^−/−^ mice) results in reduced bacterial loads in the lung. This reduction was preceded by an accelerat