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Quantal analysis of suppressing action of baclofen on mossy fiber synapses in guinea pig hippocampus

โœ Scribed by Kazunari Hirata; Satsuki Sawada; Chosaburo Yamamoto


Book ID
115802583
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
668 KB
Volume
578
Category
Article
ISSN
0006-8993

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The action of 2-amino-4-phosphonobutyric acid (APB) on mossy fiber-induced excitation in CA3 neurons was studied in vitro with thin sections of guinea pig hippocampus. D- and DL-APB suppressed field potentials induced in regio CA3 by granular layer stimulation. Threshold concentration of DL-APB to i

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## Abstract Although adenosine has been considered to depress release of neurotransmitter in central synapses, evidence for this notion is circumstantial. To obtain more direct and quantitative evidence, the suppressing action of adenosine on transmission through the mossy fiber synapse was examine