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Quantal analysis of 5-hydroxytryptamine release from mouse pancreatic β-cells

✍ Scribed by Paul A. Smith; Peter Proks; Frances M. Ashcroft

Book ID
111118548
Publisher
Cambridge University Press
Year
1999
Tongue
English
Weight
296 KB
Volume
521
Category
Article
ISSN
0022-3751

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✍ Ludger H. Rolf; Günter G. Brune 📂 Article 📅 1981 🏛 Springer 🌐 English ⚖ 312 KB

Platelets of healthy human subjects were incubated with 5-hydroxytryptamine (5-HT) followed by a second incubation with either beta-endorphin (beta-end) or the combination of beta-end and naloxone. beta-End (300 pg/ml) reduced the levels of 5-HT to 50% of initial values within 15-40 min. After 40-80