## Abstract ## Background Alzheimer's disease and related syndromes have heavy social and human consequences for the patient and his family. Beyond the neuropsychiatric effects of specific therapies for dementia, one of today's challenges is the quality of life for both patients and their informal
Quality of life in dementia: care recipient and caregiver perceptions of quality of life in dementia: the LASER-AD study
✍ Scribed by Juanita Hoe; Cornelius Katona; Martin Orrell; Gill Livingston
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 94 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0885-6230
- DOI
- 10.1002/gps.1786
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Background
Quality of Life (QoL) is a key outcome in dementia.
Aim
To compare care recipients' (CR) and caregivers' (CG) views on CRs' QoL and identify determinants.
Methods
CRs and CGs completed the Quality of Life ‐ Alzheimer's Disease (QOL‐AD) scale.
Results
One hundred and ninety‐one CR/CG dyads were interviewed. There were differences between determinants of the CRs and CGs views about QoL. Family‐CGs rated CRs' QoL higher when CRs had fewer depressive symptoms, less irritability, less apathy, less daily living impairment and lived at home. Fewer depressive symptoms, living at home and taking acetylcholinesterase‐inhibitors (AChEI) predicted higher CR rated QoL.
Conclusion
Proxy ratings in dementia do not replicate CRs' views of QoL. This is the first study to employ a validated QoL measure for people with dementia taking AChEIs. Randomised controlled trials are needed before drawing conclusions about their effect on QoL. Interpretation of correlations between QoL and symptoms should be cautious as QoL is designed to reflect the impact of psychological and physical symptoms. Copyright © 2007 John Wiley & Sons, Ltd.
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