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Quality control of colloid and particulate99mTc-labeled radiopharmaceuticals

✍ Scribed by Elias P. Belkas; Spyridon Archimandritis

Publisher
Springer
Year
1979
Tongue
English
Weight
235 KB
Volume
4
Category
Article
ISSN
0340-6997

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✦ Synopsis

A procedure for the radiochemical purity control of colloid and particulate 99mTc-labeled radiopharmaceuticals is described. The proposed technique is based on the use of two chromatograms, using in both, 15% H3PO4 as solvent and impregnated glass fiber media (Gelman ITLC type SG) as stationary phase. A pretreatment of the radiopharmaceutical with 6 N NaOH is involved prior to one chromatographic run. The procedure is fast and the different species (free pertechnetate, 99mTc-Sn-colloid and labeled 99mTc) in a 99mTc-labeled radiopharmaceutical can be determined accurately and with reliability.

πŸ“œ SIMILAR VOLUMES

Radiochemical quality control of99mTc-la
Radiochemical quality control of99mTc-labeled radiopharmaceuticals
✍ E. K. J. Pauwels; R. I. J. Feitsma πŸ“‚ Article πŸ“… 1977 πŸ› Springer 🌐 English βš– 566 KB

Recognizing the fact that each nuclear medicine facility should be able to perform simple radiochemical quality tests on currently used radiopharmaceuticals, this study was undertaken to evaluate a number of radiochromatographic methods. No single ideal method exists to assess the radiochemical comp