Quality assurance in RT-PCR-based BCR/ABL diagnostics – results of an interlaboratory test and a standardization approach

Diagnostic DHPLC Quality Assurance (DDQA

Diagnostic DHPLC Quality Assurance (DDQA): A collaborative approach to the generation of validated and standardized methods for DHPLC-based mutation screening in clinical genetics laboratories

✍ Els Schollen; Elisabeth Dequeker; Shirley McQuaid; Bruno Vankeirsbilck; Genevièv 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 339 KB

Genetic testing in a clinical diagnostic environment must be subject to rigorous quality control procedures, in order to ensure consistency and accuracy of results. Denaturing high performance liquid chromatography (DHPLC) has become a standard prescreening tool for mutation detection, offering very