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Qualitative sex differences in κ-opioid analgesia in mice are dependent on age

✍ Scribed by Wendy F Sternberg; Jennifer Ritchie; Jeffrey S Mogil


Book ID
116766696
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
95 KB
Volume
363
Category
Article
ISSN
0304-3940

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The administration of the GABA-blocking agents picrotoxin and bicuculline to adult (2.5-3 months old) CBA/HZgr mice resulted in the appearance of convulsions, the occurrence and/or lethality of which was greater in males than in females. The latency of picrotoxin-induced convulsions was also shorter