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Qualitative and quantitative analysis of drug interactions: Fritillary mediating the transport of alkaloids in caco-2 cells by p-glycoprotein

✍ Scribed by Ma, Jingwei; Kan, Hong; Ma, Yinghui; Men, Lihui; Pi, Zifeng; Liu, Zhiqiang; Liu, Zhongying

Book ID
125386646
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
720 KB
Volume
30
Category
Article
ISSN
1005-9040

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To investigate the potential interaction between selected ingredients of grapefruit juice and, the transport of talinolol, a P-gp substrate, across Caco-2 cells monolayers was determined in the absence and presence of distinct concentrations of grapefruit juice, bergamottin, 6 0 ,7 0 -dihydroxyberga