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Qualification of new biomarkers for drug-induced liver injury in a human cohort

✍ Scribed by Petra Thulin; Marcus Gry; Gunnar Nordahl; Getnet Yimer; Stig Linder; Eleni Aklillu; Björn Glinghammar; Ina Schuppe-Koistinen


Book ID
116925147
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
85 KB
Volume
211
Category
Article
ISSN
0378-4274

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## Abstract Limitations of existing biomarkers to detect liver injury in experimental animals highlight the need for additional tools to predict human toxicity. The utility of cytochrome c (cyt c) as a biomarker in serum and urine was evaluated in two rodent liver injury models. Adult Sprague–Dawle