✦ LIBER ✦

QSAR Study of 2-(1-Propylpiperidin-4-yl)-1H-Benzimidazole-4-Carboxamide as PARP Inhibitors for Treatment of Cancer

✍ Scribed by Siavash Riahi; Eslam Pourbasheer; Rassoul Dinarvand; Mohammad Reza Ganjali; Parviz Norouzi

Book ID: 111368619
Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 195 KB
Volume: 72
Category: Article
ISSN: 1747-0277
DOI: 10.1111/j.1747-0285.2008.00739.x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Discovery of the Poly(ADP-ribose) Polyme

Discovery of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide (ABT-888) for the Treatment of Cancer

✍ Penning, Thomas D.; Zhu, Gui-Dong; Gandhi, Viraj B.; Gong, Jianchun; Liu, Xueson 📂 Article 📅 2009 🏛 American Chemical Society 🌐 English ⚖ 221 KB

QSAR study of 1,3–dioxo-4-methyl-2,3-dih

QSAR study of 1,3–dioxo-4-methyl-2,3-dihydro-1h-pyrrolo[3,4-c]quinolines as caspase-3 inhibitors

✍ Simant Sharma; Kamlesh Sahu; Prateek Jain; V. K. Mourya; Ram K. Agrawal 📂 Article 📅 2007 🏛 Springer-Verlag 🌐 English ⚖ 409 KB

Molecular-docking-guided 3D-QSAR studies

Molecular-docking-guided 3D-QSAR studies of substituted isoquinoline-1,3-(2H,4H)-diones as cyclin-dependent kinase 4 (CDK4) inhibitors

✍ Xiao-Yun Lu; Ya-Dong Chen; Ni-yue Sun; Yong-Jun Jiang; Qi-Dong You 📂 Article 📅 2009 🏛 Springer-Verlag 🌐 English ⚖ 344 KB

Exploration of 1-(3-chloro-4-(4-oxo-4H-c

Exploration of 1-(3-chloro-4-(4-oxo-4H-chromen-2-yl)phenyl)-3-phenylurea derivatives as selective dual inhibitors of Raf1 and JNK1 kinases for anti-tumor treatment

✍ Jin, Feng; Gao, Dan; Zhang, Cunlong; Liu, Feng; Chu, Bizhu; Chen, Yan; Chen, Yu 📂 Article 📅 2013 🏛 Elsevier Science 🌐 English ⚖ 532 KB

Synthesis of 1-(2,4-dichlorophenyl)-4-cy

Synthesis of 1-(2,4-dichlorophenyl)-4-cyano-5-(4-[11C]methoxyphenyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide ([11C]JHU75528) and 1-(2-bromophenyl)-4-cyano-5-(4-[11C]methoxyphenyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide ([11C]JHU75575) as potential radioligands for PET imaging of cerebral cannabinoid receptor

✍ Hong Fan; Hayden T. Ravert; Daniel P. Holt; Robert F. Dannals; Andrew G. Horti 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 183 KB

## Abstract Two novel ligands for cerebral cannabinoid receptor (CB1), 1‐(2,4‐dichlorophenyl)‐4‐cyano‐5‐(4‐methoxyphenyl)‐__N__‐(piperidin‐1‐yl)‐1__H__‐pyrazole‐3‐carboxamide (JHU75528) and 1‐(2‐bromophenyl)‐4‐cyano‐5‐(4‐methoxyphenyl)‐__N__‐(piperidin‐1‐yl)‐1__H__‐pyrazole‐3‐carboxamide (JHU75575)

The Identification of 2-(1 H -Indazol-4-

The Identification of 2-(1 H -Indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2- d ]pyrimidine (GDC-0941) as a Potent, Selective, Orally Bioavailable Inhibitor of Class I PI3 Kinase for the Treatment of Cancer †

✍ Folkes, Adrian J.; Ahmadi, Khatereh; Alderton, Wendy K.; Alix, Sonia; Baker, Ste 📂 Article 📅 2008 🏛 American Chemical Society 🌐 English ⚖ 659 KB