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QSAR Study and VolSurf Characterization of Human Intestinal Absorption of Drugs

✍ Scribed by Hu Gui-Xiang; Shang Zhi-Cai; Zou Jian-Wei; Yang Guo-Ming; Yu Qing-Sen


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
472 KB
Volume
21
Category
Article
ISSN
0256-7660

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Rapid Prediction of Human Intestinal Abs
✍ Deretey, Eugen ;Feher, Miklos ;Schmidt, Jonathanβ€…M. πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 309 KB

This work describes the modeling of human intestinal absorption using one-and two-descriptor nonlinear models. Molecules with known transport mechanisms other than passive transport were removed from the dataset. The human intestinal absorption data were fitted to symmetric and asymmetric sigmoidal