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QSAR study and molecular docking on indirubin inhibitors of Glycogen Synthase Kinase-3

✍ Scribed by Luminita Crisan, Liliana Pacureanu, Alina Bora, Sorin Avram, Ludovic Kurunczi, Zeno Simon


Book ID
118016220
Publisher
SP Versita
Year
2012
Tongue
English
Weight
928 KB
Volume
11
Category
Article
ISSN
1895-1066

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QSAR study and molecular docking on indi
✍ Luminita Crisan, Liliana Pacureanu, Alina Bora, Sorin Avram, Ludovic Kurunczi, Z πŸ“‚ Article πŸ“… 2012 πŸ› SP Versita 🌐 English βš– 928 KB

## Abstract The current study describes the development of in silico models based on a novel alternative of the MTD-PLS methodology (Partial-Least-Squares variant of Minimal Topologic Difference) developed by our group to predict the inhibition of GSK-3Ξ² by indirubin derivatives. The new MTD-PLS me