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QSAR modeling of anxiolytic activity taking into account the presence of keto- and enol-tautomers by balance of correlations with ideal slopes

โœ Scribed by Toropova, Alla. ;Toropov, Andrey ;Benfenati, Emilio ;Gini, Giuseppina ;Leszczynska, Danuta ;Leszczynski, Jerzy


Book ID
111488250
Publisher
Walter de Gruyter GmbH
Year
2011
Tongue
English
Weight
576 KB
Volume
9
Category
Article
ISSN
2391-5420

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QSAR modeling of anxiolytic activity tak
โœ Toropova, Alla. ;Toropov, Andrey ;Benfenati, Emilio ;Gini, Giuseppina ;Leszczyns ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› Walter de Gruyter GmbH ๐ŸŒ English โš– 576 KB

## Abstract Optimal descriptors calculated with simplified molecular input line entry system (SMILES) have been examined as a tool for prediction of anxiolytic activity. Descriptors calculated with SMILES (a) of keto-isomers; (b) of enol-isomers; and (c) of both keto-isomers together with enol-isom