Contribution of Toll-like receptor/myelo
β
Ekihiro Seki; Hiroko Tsutsui; Yuji Iimuro; Tetsuji Naka; Gakuhei Son; Shizuo Aki
π
Article
π
2005
π
John Wiley and Sons
π
English
β 349 KB
Toll-like receptors (TLRs) act as innate immune signal sensors and play central roles in host defense. Myeloid differentiation factor (MyD) 88 is a common adaptor molecule required for signaling mediated by TLRs. When the receptors are activated, cells bearing TLRs produce various proinflammatory cy