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PZ-51 (Ebselen) in vivo protection against Adriamycin-induced mouse cardiac and hepatic lipid peroxidation and toxicity

✍ Scribed by Chris A. Pritsos; Michael Sokoloff; Daniel L. Gustafson


Book ID
115782876
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
385 KB
Volume
44
Category
Article
ISSN
0006-2952

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## Abstract Captopril and enalapril—angiotensin‐converting enzyme (ACE) inhibitors—were evaluated for their antioxidative protective action against adriamycin‐induced cardiac and hepatic toxicity. Rats were treated with either captopril (10 mg kg^−1^) or enalapril (2 mg kg^−1^) intragastrically (i.