Ineffective erythropoiesis in the spleen
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Shin Aizawa; Urara Kohdera; Masaki Hiramoto; Yutaka Kawakami; Ken-ichi Aisaki; Y
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Article
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2003
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John Wiley and Sons
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English
⚖ 147 KB
👁 2 views
## Abstract In this study, possible adverse effects of pyruvate kinase (PK) deficiency on the maturation of erythroid progenitors were investigated. A 4‐year‐old Japanese girl with severe PK deficiency underwent splenectomy to reduce her need for blood transfusions. The spleen was examined a histol