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Pyruvate kinase deficiency associated with severe liver dysfunction in the newborn

✍ Scribed by Martine F. Raphaël; Richard Van Wijk; Joachim J. Schweizer; Netteke A.Y. Schouten-van Meeteren; Angelika Kindermann; Wouter W. van Solinge; Frans J. Smiers


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
210 KB
Volume
82
Category
Article
ISSN
0361-8609

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✍ Shin Aizawa; Urara Kohdera; Masaki Hiramoto; Yutaka Kawakami; Ken-ichi Aisaki; Y 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 147 KB 👁 2 views

## Abstract In this study, possible adverse effects of pyruvate kinase (PK) deficiency on the maturation of erythroid progenitors were investigated. A 4‐year‐old Japanese girl with severe PK deficiency underwent splenectomy to reduce her need for blood transfusions. The spleen was examined a histol