Pyruvate kinase: A model allosteric enzyme for demonstration of structure-function relationships
β Scribed by M. Kapoor
- Book ID
- 107770000
- Publisher
- Elsevier Science
- Year
- 1976
- Tongue
- English
- Weight
- 575 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0020-711X
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Pyruvate kinase (ATP: pyruvate phosphotransferase, EC 2.7.1.40) is a key glycolytic enzyme that catalyzes the formation of pyruvate and ATP from phoshoenolpyruvate and ADP. The enzyme from several non-plant sources has been purified and studied extensively [8,9,12,15,18]. Most of these enzymes are h
## Abstract In a significant work, Dobson and Doig (J Mol Biol 2003, 330, 771) illustrated protein prediction as enzymatic or not from spatial structure without resorting to alignments. They used 52 protein features and a nonlinear support vector machine model to classify more than 1000 proteins co