๐”– Bobbio Scriptorium
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Pyruvate and citrate metabolism in the muscle tissue ofAscaris lumbricoides

โœ Scribed by J. Barrett


Book ID
104751960
Publisher
Springer-Verlag
Year
1978
Tongue
English
Weight
320 KB
Volume
55
Category
Article
ISSN
1432-1955

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โœฆ Synopsis


Aconitase and NAD linked isocitrate dehydrogenase were present in Ascaris lumbricoides muscle at only very low activities, whilst there were significant levels of citrate synthase, NADP linked isocitrate dehydrogenase, 2-oxoglutarate dehydrogenase and succinic thiokinase. Pyruvate dehydrogenase was present in A. lumbricoides muscle at levels comparable with mammalian tissues and results suggest that it is modulated via a phosphotransferase/phosphatase system. The tricarboxylic acid cycle intermediates, citrate, isocitrate and 2-oxoglutarate were all detected in freeze clamped muscle, but their steady state levels were considerably lower than those found in mammalian tissues.


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