Pyruvate and citrate metabolism in the muscle tissue ofAscaris lumbricoides
โ Scribed by J. Barrett
- Book ID
- 104751960
- Publisher
- Springer-Verlag
- Year
- 1978
- Tongue
- English
- Weight
- 320 KB
- Volume
- 55
- Category
- Article
- ISSN
- 1432-1955
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โฆ Synopsis
Aconitase and NAD linked isocitrate dehydrogenase were present in Ascaris lumbricoides muscle at only very low activities, whilst there were significant levels of citrate synthase, NADP linked isocitrate dehydrogenase, 2-oxoglutarate dehydrogenase and succinic thiokinase. Pyruvate dehydrogenase was present in A. lumbricoides muscle at levels comparable with mammalian tissues and results suggest that it is modulated via a phosphotransferase/phosphatase system. The tricarboxylic acid cycle intermediates, citrate, isocitrate and 2-oxoglutarate were all detected in freeze clamped muscle, but their steady state levels were considerably lower than those found in mammalian tissues.
๐ SIMILAR VOLUMES
The effects of temperature on the kinetics of the different cytoplasmic malate dehydrogenases which are present during the life cycle of Ascaris lumbricoides were studied. Aerobic development of the eggs occurs below 32"C, whereas anaerobic energy metabolism in adults occurs at 38-40ยฐC. Eggs develop