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Pyrrolidinedithiocarbamate induces apoptosis in cerebellar granule cells: involvement of AP-1 and MAP kinases

✍ Scribed by Carola Porcile; Sabrina Stanzione; Patrizia Piccioli; Adriana Bajetto; Simone Barbero; Michela Bisaglia; Rudy Bonavia; Tullio Florio; Gennaro Schettini

Book ID: 117409894
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 236 KB
Volume: 43
Category: Article
ISSN: 0197-0186
DOI: 10.1016/s0197-0186(02)00197-3

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## Abstract The nuclear factor (NF)‐κB family of transcription factors plays important roles in the regulation of many activities of neuronal cells, such as synaptic transmission, inflammation, neuroprotection, and neurotoxicity. In resting cells, NF‐κB activity is present both in the cytoplasm, as