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Pyrinodemins E and F, new 3-alkylpyridine alkaloids from sponge Amphimedon sp.

✍ Scribed by Ken’ichi Kura; Takaaki Kubota; Jane Fromont; Jun’ichi Kobayashi

Book ID
104005101
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
418 KB
Volume
21
Category
Article
ISSN
0960-894X

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✦ Synopsis

Two new 3-alkylpyridine alkaloids, pyrinodemins E (1) and F (2), were isolated from an Okinawan marine sponge Amphimedon sp. and the structures of 1 and 2 were elucidated on the basis of spectroscopic data. Pyrinodemins E (1) and F (2) were novel 3-alkylpyridine alkaloids possessing a 4-(methoxyamino)piperidinone moiety and an indol-3-glyoxylamide moiety, respectively. Pyrinodemin E (1) showed cytotoxicity against P388 and L1210 murine leukemia cells.

📜 SIMILAR VOLUMES

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✍ Keiko Hirano; Takaaki Kubota; Masashi Tsuda; Yuzuru Mikami; Jun'ichi Kobayashi 📂 Article 📅 2000 🏛 John Wiley and Sons ⚖ 27 KB 👁 1 views

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