Pyrimidines LIX. Hydroxytetrahydropyrimidines — intermediates in the synthesis of pyrimidines from α,Β-unsaturated carbonyl compounds and amidines
✍ Scribed by A. L. Vais; V. P. Mamaev
- Book ID
- 112327518
- Publisher
- Springer US
- Year
- 1977
- Tongue
- English
- Weight
- 402 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0009-3122
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📜 SIMILAR VOLUMES
N-t-Butylacetamidines 1 on heating with methyl vinyl ketone, acrolein or crotonaldehyde gave the 2,3-dihydropyridine derivatives 4, 5 or 6 via N-alkylation of the acetamidines 1. Reaction of amidines 1 with phenyl 1-propenyl ketone, benzalacetone or chalcone gave 3,4-dihydropyridine derivatives 8, 9
## Abstract The α,β‐unsaturated thiolesters listed in Table I have been prepared by treating a mixture of a carbonyl compound and boron trifluoride with an acetylenic thioether (see reaction scheme 2). Good yields are obtained when ethers are used as solvents. The configuration of the esters prepar