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Pyrimidine derivatives and related compounds. Part 47. A new synthesis of xanthines and pyrrolo[3,2-d]pyrimidines by intramolecular cyclisation of 6-substituted 5-nitrouracil derivatives

โœ Scribed by Hirota, Kosaku; Sugiyama, Tadashi; Kitade, Yukio; Senda, Shigeo; Maki, Yoshifumi


Book ID
119956823
Publisher
Royal Society of Chemistry
Year
1984
Weight
688 KB
Category
Article
ISSN
1472-7781

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Pyrimidine Derivatives and Related Compo
โœ Mohamed Helmi Elnagdi; Mohamed Mohamed Mohamed Sallam; Mohamed Ajmal Mohamed Ili ๐Ÿ“‚ Article ๐Ÿ“… 1975 ๐Ÿ› John Wiley and Sons ๐ŸŒ German โš– 705 KB

## Abstract 3,5โ€Diaminoโ€4โ€phenylazoโ€pyrazoles (**1aโ€“1c**) react with acetylacetone and with ethyl acetoacetate to yield the corresponding pyrazolo[1,5โ€a]pyrimidine derivatives **2aโ€“2c** and **3aโ€“3c**, respectively. Whereas **1aโ€“1c** add readily to methyl acrylate yielding the 4,5,6,7โ€tetrahydropyr