𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Pyrimidine 5′-nucleotidase activity in normal and deficient human lymphoblastoid cells

✍ Scribed by D. A. Hopkinson; D. M. Swallow; A. Marinaki; E. H. Harley

Publisher
Springer
Year
1990
Tongue
English
Weight
588 KB
Volume
13
Category
Article
ISSN
0141-8955

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Electrophoretic and kinetic studies of h
Electrophoretic and kinetic studies of human erythrocytes deficient in pyrimidine 5′-nucleotidase
✍ Raymonde Rosa; Henri Rochant; Bernard Dreyfus; Colette Valentin; Jean Rosa 📂 Article 📅 1977 🏛 Springer 🌐 English ⚖ 418 KB

A new case of a defect in red cell pyrimidine 5'-nucleotide (P5N) activity was found in a large family from Guadeloupe in the West Indies. The propositus presented a characteristic hemolytic anemia with red cell basophilic stippling, an increased GSH level, and a shift of the peak in absorbance of n

Kinetic and electrophoretic studies of h
Kinetic and electrophoretic studies of human erythrocytes deficient in pyrimidine 5′-nucleotidase
✍ Kenji Shinohara; Kouichi R. Tanaka 📂 Article 📅 1979 🏛 Springer 🌐 English ⚖ 292 KB

The mutant enzyme of a patient with hereditary pyrimidine 5'-nucleotidase deficiency was analyzed biochemically. Partially purified by DEAE-Sephadex and concentrated by ultrafiltration, the enzyme had a high Km for the substrate uridine monophosphate. Utilization of the substrate cytidine monophosph

Mutagenesis by apurinic sites in normal
Mutagenesis by apurinic sites in normal and ataxia telangiectasia human lymphoblastoid cells
✍ Donna K. Klinedinst; Norman R. Drinkwater 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 1019 KB

## Abstract We used a shuttle vector based on the Epstein‐Barr virus origin of plasmid replication (oriP) to determine the types of mutations induced by depurination in human cells. Plasmid DNA was incubated at pH 2 at 40°C for various times to induce up to 20 apurinic (AP) sites per 9.7‐kb plasmid