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Pyrimethamine/sulfadoxine still a good bet for malaria prevention


Book ID
120847188
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2007
Weight
121 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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Artemisinin derivatives, such as artesunate, have a short half-life and very rapid anti-malarial activity. Theoretically, using such agents in conjunction with well-established anti-malarial drugs such as sulfadoxine-pyrimethamine may reduce the rate of drug resistance. Such a combination has not pr

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Chloroquine can no longer be recommended as the first-line treatment for falciparum malaria in several parts of Africa, given the increasing resistance of Plasmodium falcipanrm to this drug. The sulfadoxinepyrimethamine combination (SP) is obviously an alternative candidate, that has already been se